News Letter
Information about Larengyal Carcinoma


Laryngeal cancer is one of the 10 leading causes of cancer in Indian men. Laryngeal cancer is the ninth and seventh most common cause of cancer in males in Asia and India respectively. In 2012, an estimated 25,446 new case were diagnosed and 17,560 Indians lost their lives due to Laryngeal cancer. In India, the incidence of Laryngeal cancer has been reported to be 1.26-8.18 per 100,000 population.


Hypopharyngeal cancers arise from the mucosa of one of the three anatomical subsites of the hypopharynx and are characterised by advanced disease at presentation mainly because the hypopharynx, laying outside the glottis and being a silent area, allows tumors to grow for a substantial period of time before symptoms occur.


Hypopharyngeal cancer is a rare disease representing about 0.5% of all human malignancies with an incidence of less than 1 per 100,000 population and constituting only 3%–5% of all head and neck cancers .Hypopharyngeal cancers are more common in men than in women. Increased incidence in males of over 2.5:100,000 are seen in India, Brazil, Central and Western Europe and decreased incidence under 0.5:100,000 in Eastern Asia, Africa and Northern Europe. The incidence in women is as high as 0.2:100,000 in the majority of the countries, except for India (1:100,000)


Laryngeal cancer produces loss of voice and radiotherapy to Larynx can further complicate voice loss. Rasayana Therapy has shown excellent results in preserving voice of the patient and preventing disease progression .Rasayana Therapy has shown excellent results in helping patients to tolerate chemotherapy as well as radiotherapy.


Rasayana Therapy increases patients quality of life and significantly reduces his symptoms. Rasayana Therapy also improves patient’s survival by several folds and also cause tumor regression. In successfully treated cases Rasayana Therapy significantly reduces the risk of a relapse.


Hoarseness or voice change for a long time.

A sore throat that does not go away for a long time.

Constant cough.

Pain during swallowing.


Trouble breathing.

A mass in neck.


Chewing Tobacco.

Drinking alcohol.

Poor nutrition.


Workplace exposure- Long and intense exposure to wood dust, paint, fumes, petroleum, plastics and textile industries are risk for Laryngeal and Hypopharyngeal cancers.

Gastroesophageal reflux disease.


Fibre optic endoscopy, fine needle aspiration (FNAC)/core biopsy:-Diagnosis of head and neck cancer will normally include clinical examination by a doctor, fibre optic endoscopy, fine needle aspiration (FNAC)/core biopsy of any neck masses, followed by further examination under anaesthetic with additional biopsies if needed.


Computerized tomography (CT)/PET scan /Magnetic resonance imaging (MRI) scan-Patients with confirmed malignancy will also undergo for scan to determine stage of cancer. 


Conventional Treatment options are surgery, radiotherapy, chemotherapy  or a combination of these. Selection of treatment depends on various disease related factors like disease site, stage, anatomical accessibility of the tumor and overall well being of the patient.


1.Surgery- Current surgical techniques employ primary closure where possible, but can allow for extensive resections by performing immediate reconstructions using free flaps from skin, fascia, muscle or bone.


This is often the treatment of choice in more advanced lesions,i.e.T3/T4 Tumours.


2.Radiation therapy-It can be used as the primary treatment or in the adjuvant postoperative setting. Indications and technique will depend on anatomical location of the tumor. The major potential advantage of this therapy is functional preservation, particularly of speech and swallowing. Acute skin reactions, mucosites are more common side effects of radiotherapy.


3.Chemotherapy-Agents such as 5-flurouracil, cisplatin and methotreaxate can produce high response rates, however, responses tend to be short lived, regrowth is often rapid, and there is no evidence to show any survival benefit. Chemotherapy in the neoadjuvant setting and concurrent with radiotherapy along with newer agents are the subjects of current clinical trials. Myelosuppression and mucositis are the most common side effects of this therapy.

Global Appointment

Dr. Bendale will be soon available at Dubai for offering consultation to patients.Patients desirous of having an appointment can contact us at following mail id

Netherland and Belgium

Dr. Bendale will be soon available at Netherland for offering consultation to patients.Patients desirous of having an appointment can contact us at following mail id


Dr. Bendale will be soon available at London for offering consultation to patients.Patients desirous of having an appointment can contact us at following mail id