News Letter
Information about Ovarian Cancer

 

Ovaries are reproductive glands found  in females. One ovary is on each side of the uterus in the pelvis. When cancer begins in the ovaries it is called as Ovarian cancer. The Ovaries are the main source of the female hormones estrogen and progesterone.

 

Ovarian cancer is the tenth most commonly diagnosed cancer among Indian women, with 363 new cases diagnosed during 2012. However, it is the fifth leading cause of cancer death among women in Indian, claiming 320 lives during 2012 alone. Ovarian cancer causes more deaths than any other cancer of the female reproductive system.

 

The ovaries are made up of 3 main kinds of cells. Each type of cell can develop into a different type of tumor:

 

1.Epithelial cell

2.Germ cell

3.Stroma

 

 

 

Ovarian cancer incidence is on raise and one of the main reasons as per Ayurveda is its relation to various lifestyle factors which interfere with natural functioning of reproductive systems. Our approach towards treating Ovarian cancer lies in treating the etiological factors and correcting the imbalance. We believe that killing the cancerous cells through cytotoxic drugs can never be a complete treatment for any cancer. And thus in treating Ovarian cancer also we believe in restoring homeostasis in the body and stimulating the immunity to tackle with tumor naturally. Moreover just dealing with tumor is not sufficient as cancer is not just tumor it’s a Pathology in the body mainly related to inflammation which leads to cancer, its spread and even its relapse. Thus out treatment targets this pathology and also stimulates the immune mechanism thereby significantly reducing the risk of cancer spread and relapse.

 

Our treatment also helps to overcome the painful symptoms in a short span of few weeks and also improves patients quality of life. It also acts on various psychological factors and takes the patient out from depression and anxiety, thereby increasing patients participation in the treatment .

 . Bloating.

 . Pelvic or abdominal pain.

 . Trouble eating or feeling full quickly.

 . Urinary symptoms such as urgency (always feeling like you have to go) or frequency (having to go often).

 . Fatigue.

 . Upset stomach.

 . Back pain.

 . Pain during sex.

 . Constipation.

 . Menstrual changes.

 . Abdominal swelling with weight loss.

 

The most important risk factor is a strong family history of Breast or Ovarian cancer. The person who had Breast cancer, or who have tested positive for inherited mutations in BRCA2 genes are at increased risk. Studies indicate that preventive surgery to remove the ovaries and fallopian tubes in these women can decrease the risk of Ovarian cancer.

 

Some additional risk factors include:

 

Age- The risk of developing Ovarian cancer increases with age. Ovarian cancer is rare in women younger than 40. Most Ovarian cancers develop after menopause. Half of all Ovarian cancers are found in the older age.

 

Smoking-Tobacco smoking increases risk of mucinous Ovarian cancer (cancer that begins in the outer lining of the ovary).

 

Other medical conditions- such as pelvic inflammatory disease and a genetic condition called hereditary nonpolyposis colorectal cancer (also called Lynch syndrome), may indicate an increased risk for Ovarian cancer.

 

History of hormone replacement therapy (HRT)- Studies have shown that the use of estrogen alone as menopausal hormone therapy can increase risk for developing Ovarian cancer.

 

Obesity- Obese women have a higher risk of developing Ovarian cancer.

 

Reproductive history- Women who have been pregnant and carried it to term before age 26 have a lower risk of Ovarian cancer than women who have not. Women who have their first full-term pregnancy after age 35 or who never carried a pregnancy to term have a higher risk of Ovarian cancer.

 

Breastfeeding may lower the risk even further.

 

Birth control - Women who have used oral contraceptives (also known as birth control pills or the pill) have a lower risk of Ovarian cancer.

 

Fertility drugs- In some studies, researchers have found that using the fertility drug clomiphene citrate  for longer than one year may increase the risk of developing Ovarian tumors.

 

Androgens -Androgens are male hormones. Danazol, a drug that increases androgen levels, was linked to an increased risk of ovarian cancer in a small study. In a larger study, this link was not confirmed, but women who took androgens were found to have a higher risk of ovarian cancer.

 

Estrogen therapy and hormone therapy.

Some recent studies suggest women using estrogens after menopause have an increased risk of developing ovarian cancer. The risk seems to be higher in women taking estrogen alone (without progesterone) for many years (at least 5 or 10). The increased risk is less certain for women taking both estrogen and progesterone.

 

Family history of ovarian cancer, breast cancer, or colorectal cancer

Ovarian cancer can run in families.

 

Personal history of breast cancer

If you have had breast cancer, you might also have an increased risk of developing ovarian cancer

 

1.Ultrasound or Computed tomography (CT) scans of Abdomen-To look any pelvic mass

 

2.Chest x-ray- and Positron emission tomography (PET) scan- This test can be helpful in detecting cancer at micro-level. It is useful in detecting spread of cancer to any other organs in the body.

 

3.Biopsy- In patients with Ascites (fluid buildup inside the abdomen), samples of the fluid can also be used to diagnose the cancer.

 

4.Blood tests & Tumor markers – Raised tumors markers are indicative of presence of cancer in the body -CA-125 test.-The presence of a solid pelvic mass or a multiloculated cystic mass with CA 125 over 100 U/ml is most likely to indicate an Ovarian cancer.

 

Human chorionic gonadotropin (HCG)/Alpha-fetoprotein (AFP), and/or Lactate dehydrogenase (LDH). –In women under age 35 years should also be measured these factors as these can be raised in malignant teratomas and germ cell tumors.

 

After the diagnostic tests are done, your doctor will recommend 1 or more treatment options depending on your type and stage of cancer.

 

The available treatments for ovarian cancer are:

 

Surgery- The main principle of treatment is to remove all possible visible tumour. This usually involves performing a hysterectomy, BSO and omentectomy.

 

Chemotherapy/Hormone therapy/Targeted Therapy- According to stage of cancer after recovery from surgery Chemotherapy/Hormone therapy/Targeted Therapy may started. Cyclophosphamide or Cyclophosphamide and doxorubicin or newly discovered drugs, the taxens are commonly used to treat tumors but all these drugs have some toxic side effects.

 

Radiation therapy – It may be used to direct treatment at a solitary pelvic recurrence or to treat secondaries.

Global Appointment
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Dr. Bendale will be soon available at Dubai for offering consultation to patients.Patients desirous of having an appointment can contact us at following mail id care@rasayucancerclinic.com

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